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Prisma Health moves large scale COVID-19 mass vaccination site from Gamecock Park to the Colonial Life Arena

Friday, April 30, 2021

Move continues strong partnership with UofSC and South Carolina National Guard

COLUMBIA, SC—Prisma Health will move its large-scale COVID-19 vaccination site from Gamecock Park to an indoor walk-in location at the Colonial Life Arena. The move, in partnership with the University of South Carolina (UofSC) and the South Carolina National Guard, is designed to help accommodate the summer temperatures. The last day for the drive-thru site at Gamecock Park is Saturday, May 1. The Colonial Life Arena vaccination site will open 8 a.m., Wednesday, May 5.

Community members who received first-dose vaccinations at Gamecock Park were given instructions on the change and how to get their second shot at the new location. The new site also will feature an adjustment to the operating hours, with the addition of evening hours to help those who work past 5 p.m. 

Details on the Prisma Health Colonial Life Arena Vaccination Site: 

  • Located inside the Colonial Life Arena, please arrive at 816 Devine Street (for parking).
  • The vaccination site is open
    • Monday–Tuesday, 11 a.m.–7 p.m.
    • Wednesday–Saturday, 8 a.m.–5 p.m.
  • Community members can continue to register for their vaccinations directly through myChart at or call Prisma Health COVID-19 hotline at 1-833-2-PRISMA.
  • Same-day appointments are available every day.
  • There will be South Carolina National Guardsmen and staff outside to direct the community on where to parking.
  • Shuttles to the door will be available.

Prisma Health has administered more than 370,000 vaccines as of April 28. As the largest vaccine provider of Pfizer vaccine in South Carolina, Prisma Health is focused on helping build community immunity and is extremely proud of its partnership with UofSC and SC National Guard on both sites.

“The Prisma Health team is dedicated to caring for our community during this pandemic and every day. Throughout the entire COVID-19 response, we are proud of everything our team members, nurses, and physicians have given to help our community,” said Rick Scott, MD, Prisma Health’s chief clinical officer in the Midlands and the co-chair of its COVID-19 vaccine task force “We could not have been successful without our partnership with UofSC and the South Carolina National Guard. Their support has been an invaluable part of our efforts. It takes all of us working together to make things happen, and there is much left to do!" 

UofSC’s partnership to help coordinate and provide the host sites has been key to the ongoing success at Gamecock Park and the transition to Colonial Life Arena. UofSC President Bob Caslen said, “Part of our university’s mission is to address pressing health issues throughout and state and in underserved communities, so we’re pleased to partner with Prisma Health on this important initiative to help protect members of our community.”

For more information about Prisma Health’s vaccination process and its vaccination sites, visit

About Prisma Health

Prisma Health is a not-for-profit health company and the largest healthcare system in South Carolina. With nearly 30,000 team members, 18 acute and specialty hospitals, 2,947 beds and more than 300 outpatient sites with nearly 2,000 physicians, Prisma Health serves more than 1.2 million unique patients annually in its 21-county market area that covers 50% of South Carolina. Prisma Health’s goal is to improve the health of all South Carolinians by enhancing clinical quality, the patient experience and access to affordable care, as well as conducting clinical research and training the next generation of medical professionals. For more information, visit

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